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The sputum transcriptome better predicts COPD exacerbations after the withdrawal of inhaled corticosteroids than sputum eosinophils

INTRODUCTION: Continuing inhaled corticosteroid (ICS) use does not benefit all patients with COPD, yet it is difficult to determine which patients may safely sustain ICS withdrawal. Although eosinophil levels can facilitate this decision, better biomarkers could improve personalised treatment decisi...

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Detalles Bibliográficos
Autores principales: Ditz, Benedikt, Sarma, Aartik, Kerstjens, Huib A.M., Liesker, Jeroen J.W., Bathoorn, Erik, Vonk, Judith M., Bernal, Victor, Horvatovich, Peter, Guryev, Victor, Caldera, Saharai, Langelier, Chaz, Faiz, Alen, Christenson, Stephanie A., van den Berge, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255541/
https://www.ncbi.nlm.nih.gov/pubmed/34235210
http://dx.doi.org/10.1183/23120541.00097-2021