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ctDNA Clearance and Radiographic Resolution of Disease in Response to Dual Checkpoint Inhibition in Metastatic Microsatellite Stable Colorectal Cancer with a High Tumor Mutation Burden

Immunotherapy (IO) has increasingly been demonstrated to provide therapeutic benefit to patients with metastatic colorectal cancer (mCRC). However, only a subset of mCRC tumors respond to IO. Monitoring response with tumor biomarkers like carcinoembryonic antigen (CEA) has been challenging in patien...

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Detalles Bibliográficos
Autores principales: Schneider, Charles J., Krainock, Michael, Malashevich, Allyson Koyen, Malhotra, Meenakshi, Olshan, Perry, Billings, Paul R., Aleshin, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255721/
https://www.ncbi.nlm.nih.gov/pubmed/34248549
http://dx.doi.org/10.1159/000516190