Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation

The circadian clock is a biological timekeeper that operates through transcription–translation feedback loops in mammals. Cryptochrome 1 (CRY1) and Cryptochrome 2 (CRY2) are highly conserved core clock components having redundant and distinct functions. We recently identified the CRY1- and CRY2-sele...

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Detalles Bibliográficos
Autores principales: Miller, Simon, Srivastava, Ashutosh, Nagai, Yoshiko, Aikawa, Yoshiki, Tama, Florence, Hirota, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255803/
https://www.ncbi.nlm.nih.gov/pubmed/34172584
http://dx.doi.org/10.1073/pnas.2026191118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255803/
https://www.ncbi.nlm.nih.gov/pubmed/34172584
http://dx.doi.org/10.1073/pnas.2026191118

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