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Hypoxia-Induced Suppression of Antiapoptotic Bcl-2 Expression in Human Bladder Tumor Cells Is Regulated by Caveolin-1-Dependent Adenosine Monophosphate-Activated Protein Kinase Activity

PURPOSE: Adenosine monophosphate-activated protein kinase (AMPK) is thought to inhibit cell proliferation or promote cell death, but the details remain unclear. In this study, we propose that AMPK inhibits the expression of anti-apoptotic B-cell lymphoma 2 (Bcl-2) by relying on the hypoxia-inducible...

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Detalles Bibliográficos
Autores principales: Cho, Tae Jin, Lee, Da-Hyun, Choi, Bo-Hwa, Shinn, Helen K., Park, Chang-Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Continence Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255828/
https://www.ncbi.nlm.nih.gov/pubmed/33752282
http://dx.doi.org/10.5213/inj.2040444.222