Activation of the mitogen‐activated protein kinase ERK1/2 signaling pathway suppresses the expression of ChREBPα and β in HepG2 cells

The carbohydrate response element‐binding protein (ChREBP), a glucose‐responsive transcription factor that plays a critical role in the glucose‐mediated induction of genes involved in hepatic glycolysis and lipogenesis, exists as two isoforms: ChREBPα and ChREBPβ. However, the mechanism responsible...

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Detalles Bibliográficos
Autores principales: Li, Lan, Sakiyama, Haruhiko, Eguchi, Hironobu, Yoshihara, Daisaku, Fujiwara, Noriko, Suzuki, Keiichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255832/
https://www.ncbi.nlm.nih.gov/pubmed/34051057
http://dx.doi.org/10.1002/2211-5463.13208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255832/
https://www.ncbi.nlm.nih.gov/pubmed/34051057
http://dx.doi.org/10.1002/2211-5463.13208

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