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Molecular dynamics provides new insights into the mechanism of calcium signal transduction and interdomain interactions in cardiac troponin

Understanding the regulation of cardiac muscle contraction at a molecular level is crucial for the development of therapeutics for heart conditions. Despite the availability of atomic structures of the protein components of cardiac muscle thin filaments, detailed insights into their dynamics and res...

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Detalles Bibliográficos
Autores principales: Genchev, Georgi Z., Kobayashi, Minae, Kobayashi, Tomoyoshi, Lu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255835/
https://www.ncbi.nlm.nih.gov/pubmed/33085832
http://dx.doi.org/10.1002/2211-5463.13009