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A Plasmodium falciparum protein tyrosine phosphatase inhibitor identified from the ChEMBL‐NTD database blocks parasite growth

Post‐translational modifications, especially reversible phosphorylation, are among the most common mechanisms that regulate protein function and biological processes in Plasmodium species. Of the Plasmodium phosphatases, phosphatase of regenerating liver (PfPRL) is secreted and is an essential phosp...

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Detalles Bibliográficos
Autores principales: Pandey, Rajan, Gupta, Priya, Mohmmed, Asif, Malhotra, Pawan, Gupta, Dinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255846/
https://www.ncbi.nlm.nih.gov/pubmed/33934569
http://dx.doi.org/10.1002/2211-5463.13171