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Sensitive and Quantitative Detection of MHC-I Displayed Neoepitopes Using a Semiautomated Workflow and TOMAHAQ Mass Spectrometry

Advances in several key technologies, including MHC peptidomics, have helped fuel our understanding of basic immune regulatory mechanisms and the identification of T cell receptor targets for the development of immunotherapeutics. Isolating and accurately quantifying MHC-bound peptides from cells an...

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Detalles Bibliográficos
Autores principales: Pollock, Samuel B., Rose, Christopher M., Darwish, Martine, Bouziat, Romain, Delamarre, Lélia, Blanchette, Craig, Lill, Jennie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255936/
https://www.ncbi.nlm.nih.gov/pubmed/34129938
http://dx.doi.org/10.1016/j.mcpro.2021.100108