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HIF-1α is a negative regulator of interferon regulatory factors: Implications for interferon production by hypoxic monocytes
Patients with severe COVID-19 infection exhibit a low level of oxygen in affected tissue and blood. To understand the pathophysiology of COVID-19 infection, it is therefore necessary to understand cell function during hypoxia. We investigated aspects of human monocyte activation under hypoxic condit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256008/ https://www.ncbi.nlm.nih.gov/pubmed/34108245 http://dx.doi.org/10.1073/pnas.2106017118 |