GRINS: Genetic elements that recode assembly-line polyketide synthases and accelerate their diversification

Assembly-line polyketide synthases (PKSs) are large and complex enzymatic machineries with a multimodular architecture, typically encoded in bacterial genomes by biosynthetic gene clusters. Their modularity has led to an astounding diversity of biosynthesized molecules, many with medical relevance....

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Detalles Bibliográficos
Autores principales: Nivina, Aleksandra, Herrera Paredes, Sur, Fraser, Hunter B., Khosla, Chaitan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256042/
https://www.ncbi.nlm.nih.gov/pubmed/34162709
http://dx.doi.org/10.1073/pnas.2100751118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256042/
https://www.ncbi.nlm.nih.gov/pubmed/34162709
http://dx.doi.org/10.1073/pnas.2100751118

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