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The OX40/OX40L Axis Regulates T Follicular Helper Cell Differentiation: Implications for Autoimmune Diseases

T Follicular helper (Tfh) cells, a unique subset of CD4(+) T cells, play an essential role in B cell development and the formation of germinal centers (GCs). Tfh differentiation depends on various factors including cytokines, transcription factors and multiple costimulatory molecules. Given that OX4...

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Detalles Bibliográficos
Autores principales: Fu, NanNan, Xie, Fang, Sun, ZhongWen, Wang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256170/
https://www.ncbi.nlm.nih.gov/pubmed/34234777
http://dx.doi.org/10.3389/fimmu.2021.670637