Elevated NTCP expression by an iPSC-derived human hepatocyte maintenance medium enhances HBV infection in NTCP-reconstituted HepG2 cells

BACKGROUND: The sodium taurocholate cotransporting polypeptide (NTCP) is a functional receptor for hepatitis B virus (HBV). NTCP-reconstituted human hepatoma cells support HBV infection, but the infection is suboptimal and no apparent HBV spread has been observed in this system. RESULTS: We found th...

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Detalles Bibliográficos
Autores principales: Li, Xinlei, Xu, Zhaohui, Mitra, Bidisha, Wang, Minghang, Guo, Haitao, Feng, Zongdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256212/
https://www.ncbi.nlm.nih.gov/pubmed/34225786
http://dx.doi.org/10.1186/s13578-021-00641-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256212/
https://www.ncbi.nlm.nih.gov/pubmed/34225786
http://dx.doi.org/10.1186/s13578-021-00641-1

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