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Elevated NTCP expression by an iPSC-derived human hepatocyte maintenance medium enhances HBV infection in NTCP-reconstituted HepG2 cells
BACKGROUND: The sodium taurocholate cotransporting polypeptide (NTCP) is a functional receptor for hepatitis B virus (HBV). NTCP-reconstituted human hepatoma cells support HBV infection, but the infection is suboptimal and no apparent HBV spread has been observed in this system. RESULTS: We found th...
Autores principales: | Li, Xinlei, Xu, Zhaohui, Mitra, Bidisha, Wang, Minghang, Guo, Haitao, Feng, Zongdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256212/ https://www.ncbi.nlm.nih.gov/pubmed/34225786 http://dx.doi.org/10.1186/s13578-021-00641-1 |
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