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The hydrogen-peroxide producing NADPH oxidase 4 does not limit neointima development after vascular injury in mice
OBJECTIVE: The NADPH oxidase Nox4 is an important source of H(2)O(2). Nox4-derived H(2)O(2) limits vascular inflammation and promotes smooth muscle differentiation. On this basis, the role of Nox4 for restenosis development was determined in the mouse carotid artery injury model. METHODS AND RESULTS...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256285/ https://www.ncbi.nlm.nih.gov/pubmed/34218201 http://dx.doi.org/10.1016/j.redox.2021.102050 |