The hydrogen-peroxide producing NADPH oxidase 4 does not limit neointima development after vascular injury in mice

OBJECTIVE: The NADPH oxidase Nox4 is an important source of H(2)O(2). Nox4-derived H(2)O(2) limits vascular inflammation and promotes smooth muscle differentiation. On this basis, the role of Nox4 for restenosis development was determined in the mouse carotid artery injury model. METHODS AND RESULTS...

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Detalles Bibliográficos
Autores principales: Buchmann, Giulia K., Schürmann, Christoph, Spaeth, Manuela, Abplanalp, Wesley, Tombor, Lukas, John, David, Warwick, Timothy, Rezende, Flávia, Weigert, Andreas, Shah, Ajay M., Hansmann, Martin-Leo, Weissmann, Norbert, Dimmeler, Stefanie, Schröder, Katrin, Brandes, Ralf P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256285/
https://www.ncbi.nlm.nih.gov/pubmed/34218201
http://dx.doi.org/10.1016/j.redox.2021.102050

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