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Scaffold compound L971 exhibits anti‐inflammatory activities through inhibition of JAK/STAT and NFκB signalling pathways

JAK/STAT and NFκB signalling pathways play essential roles in regulating inflammatory responses, which are important pathogenic factors of various serious immune‐related diseases, and function individually or synergistically. To find prodrugs that can treat inflammation, we performed a preliminary h...

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Detalles Bibliográficos
Autores principales: Li, Mengyuan, Yan, Yu, Zhang, Xinxin, Zhang, Yidan, Xu, Xiaohan, Zhang, Lei, Lu, Liangliang, Wang, Jie, Zhang, Yazhuo, Song, Qiaoling, Zhao, Chenyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256347/
https://www.ncbi.nlm.nih.gov/pubmed/34018320
http://dx.doi.org/10.1111/jcmm.16609