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A Review of the Pathophysiological Mechanisms Underlying Castration-resistant Prostate Cancer

Androgen deprivation therapy or ADT is one of the cornerstones of management of locally advanced or metastatic prostate cancer, alongside radiation therapy. However, despite early response, most advanced prostate cancers progress into an androgen unresponsive or castrate resistant state, which hithe...

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Detalles Bibliográficos
Autores principales: Crowley, Fionnuala, Sterpi, Michelle, Buckley, Conor, Margetich, Lauren, Handa, Shivani, Dovey, Zach
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256377/
https://www.ncbi.nlm.nih.gov/pubmed/34235102
http://dx.doi.org/10.2147/RRU.S264722