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Hepatic cysteine sulphinic acid decarboxylase depletion and defective taurine metabolism in a rat partial nephrectomy model of chronic kidney disease

BACKGROUND: Taurine depletion occurs in patients with end-stage chronic kidney disease (CKD). In contrast, in the absence of CKD, plasma taurine is reported to increase following dietary L-glutamine supplementation. This study tested the hypothesis that taurine biosynthesis decreases in a rat CKD mo...

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Detalles Bibliográficos
Autores principales: Abbasian, Nima, Ghaderi-Najafabadi, Maryam, Watson, Emma, Brown, Jeremy, Yu si, Li, Bursnall, Debbie, Pawluczyk, Izabella, Seymour, Anne-Marie, Bevington, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256558/
https://www.ncbi.nlm.nih.gov/pubmed/34225671
http://dx.doi.org/10.1186/s12882-021-02442-7