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Inhibition of histone deacetylase 6 suppresses inflammatory responses and invasiveness of fibroblast-like-synoviocytes in inflammatory arthritis

BACKGROUND: To investigate the effects of inhibiting histone deacetylase (HDAC) 6 on inflammatory responses and tissue-destructive functions of fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA). METHODS: FLS from RA patients were activated with interleukin (IL)-1β in the presence of in...

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Detalles Bibliográficos
Autores principales: Park, Jin Kyun, Shon, Sehui, Yoo, Hyun Jung, Suh, Dong-Hyeon, Bae, Daekwon, Shin, Jieun, Jun, Jae Hyun, Ha, Nina, Song, Hyeseung, Choi, Young Il, Pap, Thomas, Song, Yeong Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256575/
https://www.ncbi.nlm.nih.gov/pubmed/34225810
http://dx.doi.org/10.1186/s13075-021-02561-4