Characteristic mutations induced in the small intestine of Msh2-knockout gpt delta mice

BACKGROUND: Base pair mismatches in genomic DNA can result in mutagenesis, and consequently in tumorigenesis. To investigate how mismatch repair deficiency increases mutagenicity under oxidative stress, we examined the type and frequency of mutations arising in the mucosa of the small intestine of m...

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Detalles Bibliográficos
Autores principales: Aoki, Yasunobu, Ohno, Mizuki, Matsumoto, Michiyo, Matsumoto, Michi, Masumura, Kenichi, Nohmi, Takehiko, Tsuzuki, Teruhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256579/
https://www.ncbi.nlm.nih.gov/pubmed/34225823
http://dx.doi.org/10.1186/s41021-021-00196-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256579/
https://www.ncbi.nlm.nih.gov/pubmed/34225823
http://dx.doi.org/10.1186/s41021-021-00196-0

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