Cargando…
Characteristic mutations induced in the small intestine of Msh2-knockout gpt delta mice
BACKGROUND: Base pair mismatches in genomic DNA can result in mutagenesis, and consequently in tumorigenesis. To investigate how mismatch repair deficiency increases mutagenicity under oxidative stress, we examined the type and frequency of mutations arising in the mucosa of the small intestine of m...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256579/ https://www.ncbi.nlm.nih.gov/pubmed/34225823 http://dx.doi.org/10.1186/s41021-021-00196-0 |