Effect of first-line biologic initiation on glucocorticoid exposure in children hospitalized with new-onset systemic juvenile idiopathic arthritis: emulation of a pragmatic trial using observational data

BACKGROUND: Glucocorticoid exposure is a significant driver of morbidity in children with systemic juvenile idiopathic arthritis (sJIA). We determined the effect of early initiation of biologic therapy (IL-1 or IL-6 inhibition) on glucocorticoid exposure in hospitalized patients with new-onset sJIA....

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Detalles Bibliográficos
Autores principales: Peterson, Rosemary G., Xiao, Rui, Katcoff, Hannah, Fisher, Brian T., Weiss, Pamela F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256608/
https://www.ncbi.nlm.nih.gov/pubmed/34225753
http://dx.doi.org/10.1186/s12969-021-00597-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256608/
https://www.ncbi.nlm.nih.gov/pubmed/34225753
http://dx.doi.org/10.1186/s12969-021-00597-z

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