Hormonal intervention for the treatment of veterans with COVID-19 requiring hospitalization (HITCH): a multicenter, phase 2 randomized controlled trial of best supportive care vs best supportive care plus degarelix: study protocol for a randomized controlled trial

BACKGROUND: Therapeutic targeting of host-cell factors required for SARS-CoV-2 entry is an alternative strategy to ameliorate COVID-19 severity. SARS-CoV-2 entry into lung epithelium requires the TMPRSS2 cell surface protease. Pre-clinical and correlative data in humans suggest that anti-androgenic...

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ग्रंथसूची विवरण
मुख्य लेखकों: Nickols, Nicholas G., Goetz, Matthew B., Graber, Christopher J., Bhattacharya, Debika, Soo Hoo, Guy, Might, Matthew, Goldstein, David B., Wang, Xinchen, Ramoni, Rachel, Myrie, Kenute, Tran, Samantha, Ghayouri, Leila, Tsai, Sonny, Geelhoed, Michelle, Makarov, Danil, Becker, Daniel J., Tsay, Jun-Chieh, Diamond, Melissa, George, Asha, Al-Ajam, Mohammad, Belligund, Pooja, Montgomery, R. Bruce, Mostaghel, Elahe A., Sulpizio, Carlie, Mi, Zhibao, Dematt, Ellen, Tadalan, Joseph, Norman, Leslie E., Briones, Daniel, Clise, Christina E., Taylor, Zachary W., Huminik, Jeffrey R., Biswas, Kousick, Rettig, Matthew B.
स्वरूप: Online लेख मूलपाठ
भाषा:English
प्रकाशित: BioMed Central 2021
विषय:
Study Protocol
ऑनलाइन पहुंच:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256647/
https://www.ncbi.nlm.nih.gov/pubmed/34225789
http://dx.doi.org/10.1186/s13063-021-05389-0

इंटरनेट

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256647/
https://www.ncbi.nlm.nih.gov/pubmed/34225789
http://dx.doi.org/10.1186/s13063-021-05389-0

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