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PDE2 Inhibits PKA-Mediated Phosphorylation of TFAM to Promote Mitochondrial Ca(2+)-Induced Colorectal Cancer Growth
Growing evidence indicates that the dysregulation of mitochondrial calcium (Ca(2+)) plays a critical role in the growth of tumor cells, including colorectal cancer (CRC). However, the underling mechanism is not fully elucidated. In this study, the regulatory effects of mitochondrial Ca(2+) on phosph...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256694/ https://www.ncbi.nlm.nih.gov/pubmed/34235078 http://dx.doi.org/10.3389/fonc.2021.663778 |