PDE2 Inhibits PKA-Mediated Phosphorylation of TFAM to Promote Mitochondrial Ca(2+)-Induced Colorectal Cancer Growth

Growing evidence indicates that the dysregulation of mitochondrial calcium (Ca(2+)) plays a critical role in the growth of tumor cells, including colorectal cancer (CRC). However, the underling mechanism is not fully elucidated. In this study, the regulatory effects of mitochondrial Ca(2+) on phosph...

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Detalles Bibliográficos
Autores principales: Zhao, Yilin, Wang, Yaya, Zhao, Jing, Zhang, Zhaohui, Jin, Mingpeng, Zhou, Feng, Jin, Chao, Zhang, Jing, Xing, Jinliang, Wang, Nan, He, Xianli, Ren, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256694/
https://www.ncbi.nlm.nih.gov/pubmed/34235078
http://dx.doi.org/10.3389/fonc.2021.663778

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