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X-ray crystallographic studies of RoAb13 bound to PIYDIN, a part of the N-terminal domain of C-C chemokine receptor 5

C-C chemokine receptor 5 (CCR5) is a major co-receptor molecule used by HIV-1 to enter cells. This led to the hypothesis that stimulating an antibody response would block HIV with minimal toxicity. Here, X-ray crystallographic studies of the anti-CCR5 antibody RoAb13 together with two peptides were...

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Detalles Bibliográficos
Autores principales: Govada, Lata, Saridakis, Emmanuel, Kassen, Sean C., Bin-Ramzi, Ahmad, Morgan, Rhodri Marc, Chain, Benjamin, Helliwell, John R., Chayen, Naomi E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256702/
https://www.ncbi.nlm.nih.gov/pubmed/34258015
http://dx.doi.org/10.1107/S2052252521005340