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Putative hexameric glycosyltransferase functional unit revealed by the crystal structure of Acinetobacter baumannii MurG

Lipid II, the main component of the bacterial cell wall, is synthesized by the addition of UDP-N-acetylglucosamine to the UDP-N-acetylmuramic acid pentapeptide catalyzed by the glycosyltransferase MurG. Owing to its critical role in cell-wall biosynthesis, MurG is considered to be an attractive targ...

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Detalles Bibliográficos
Autores principales: Jung, Kyoung Ho, Kwon, Sunghark, Kim, Chang Min, Lee, Jun Hyuck, Park, Hyun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256705/
https://www.ncbi.nlm.nih.gov/pubmed/34258006
http://dx.doi.org/10.1107/S2052252521003729