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Structural and biophysical aspects of l-asparaginases: a growing family with amazing diversity

l-Asparaginases have remained an intriguing research topic since their discovery ∼120 years ago, especially after their introduction in the 1960s as very efficient antileukemic drugs. In addition to bacterial asparaginases, which are still used to treat childhood leukemia, enzymes of plant and mamma...

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Detalles Bibliográficos
Autores principales: Loch, Joanna I., Jaskolski, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256714/
https://www.ncbi.nlm.nih.gov/pubmed/34258001
http://dx.doi.org/10.1107/S2052252521006011