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Triosephosphate isomerase: the perfect enzyme, but how does it work?

Insights are offered on the study by Kelpšas et al. [ IUCrJ (2021). 8, 633–643], who have combined neutron and X-ray crystallography then QM (quantum mechanics) calculations on triosephosphate isomerase (TIM). The authors dissect three possible enzyme mechanisms of TIM that have arisen in the decade...

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Detalles Bibliográficos
Autor principal: Helliwell, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256717/
https://www.ncbi.nlm.nih.gov/pubmed/34257998
http://dx.doi.org/10.1107/S205225252100573X