Cargando…

Characterization of high-H(2)O(2)-tolerant bacterial cytochrome P450 CYP105D18: insights into papaverine N-oxidation

The bacterial CYP105 family is involved in secondary metabolite biosynthetic pathways and plays essential roles in the biotransformation of xenobiotics. This study investigates the newly identified H(2)O(2)-mediated CYP105D18 from Streptomyces laurentii as the first bacterial CYP for N-oxidation. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Pardhe, Bashu Dev, Do, Hackwon, Jeong, Chang-Sook, Kim, Ki-Hwa, Lee, Jun Hyuck, Oh, Tae-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256718/
https://www.ncbi.nlm.nih.gov/pubmed/34258016
http://dx.doi.org/10.1107/S2052252521005522