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Characterization of high-H(2)O(2)-tolerant bacterial cytochrome P450 CYP105D18: insights into papaverine N-oxidation
The bacterial CYP105 family is involved in secondary metabolite biosynthetic pathways and plays essential roles in the biotransformation of xenobiotics. This study investigates the newly identified H(2)O(2)-mediated CYP105D18 from Streptomyces laurentii as the first bacterial CYP for N-oxidation. Th...
Autores principales: | Pardhe, Bashu Dev, Do, Hackwon, Jeong, Chang-Sook, Kim, Ki-Hwa, Lee, Jun Hyuck, Oh, Tae-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256718/ https://www.ncbi.nlm.nih.gov/pubmed/34258016 http://dx.doi.org/10.1107/S2052252521005522 |
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