PIP-SNP: a pipeline for processing SNP data featured as linkage disequilibrium bin mapping, genotype imputing and marker synthesizing

Genome-wide association study data analyses often face two significant challenges: (i) high dimensionality of single-nucleotide polymorphism (SNP) genotypes and (ii) imputation of missing values. SNPs are not independent due to physical linkage and natural selection. The correlation of nearby SNPs i...

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Detalles Bibliográficos
Autores principales: Zhang, Wenchao, Kang, Yun, Dai, Xinbin, Xu, Shizhong, Zhao, Patrick X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256826/
https://www.ncbi.nlm.nih.gov/pubmed/34235432
http://dx.doi.org/10.1093/nargab/lqab060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256826/
https://www.ncbi.nlm.nih.gov/pubmed/34235432
http://dx.doi.org/10.1093/nargab/lqab060

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