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PIP-SNP: a pipeline for processing SNP data featured as linkage disequilibrium bin mapping, genotype imputing and marker synthesizing
Genome-wide association study data analyses often face two significant challenges: (i) high dimensionality of single-nucleotide polymorphism (SNP) genotypes and (ii) imputation of missing values. SNPs are not independent due to physical linkage and natural selection. The correlation of nearby SNPs i...
Autores principales: | Zhang, Wenchao, Kang, Yun, Dai, Xinbin, Xu, Shizhong, Zhao, Patrick X |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256826/ https://www.ncbi.nlm.nih.gov/pubmed/34235432 http://dx.doi.org/10.1093/nargab/lqab060 |
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