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Oral Vaccination Approaches for Anti-SHIV Immunity

We modified a Sabin Oral Poliovirus Vaccine (OPV) vector to permit secretion of the antigens of interest with the goal of improving anti-HIV Env humoral responses in a SHIV mucosal immunization composed of DNA and recombinant OPVs. We evaluated stimulation of systemic and mucosal cell-mediated and h...

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Detalles Bibliográficos
Autores principales: Velarde de la Cruz, Erandi, Wang, Lingyun, Bose, Deepanwita, Gangadhara, Sailaja, Wilson, Robert L., Amara, Rama R., Kozlowski, Pamela A., Aldovini, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256843/
https://www.ncbi.nlm.nih.gov/pubmed/34234789
http://dx.doi.org/10.3389/fimmu.2021.702705