Cargando…
Oral Vaccination Approaches for Anti-SHIV Immunity
We modified a Sabin Oral Poliovirus Vaccine (OPV) vector to permit secretion of the antigens of interest with the goal of improving anti-HIV Env humoral responses in a SHIV mucosal immunization composed of DNA and recombinant OPVs. We evaluated stimulation of systemic and mucosal cell-mediated and h...
Autores principales: | Velarde de la Cruz, Erandi, Wang, Lingyun, Bose, Deepanwita, Gangadhara, Sailaja, Wilson, Robert L., Amara, Rama R., Kozlowski, Pamela A., Aldovini, Anna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256843/ https://www.ncbi.nlm.nih.gov/pubmed/34234789 http://dx.doi.org/10.3389/fimmu.2021.702705 |
Ejemplares similares
-
V2 hotspot optimized MVA vaccine expressing stabilized HIV-1 Clade C envelope Gp140 delays acquisition of heterologous Clade C Tier 2 challenges in Mamu-A*01 negative Rhesus Macaques
por: Styles, Tiffany M., et al.
Publicado: (2022) -
HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge
por: Jones, Andrew T., et al.
Publicado: (2019) -
T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers
por: Arunachalam, Prabhu S., et al.
Publicado: (2020) -
The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection
por: Charles, Tysheena P., et al.
Publicado: (2021) -
Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques
por: Eudailey, Joshua A., et al.
Publicado: (2018)