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In vivo Emergence of Colistin Resistance in Carbapenem-Resistant Klebsiella pneumoniae Mediated by Premature Termination of the mgrB Gene Regulator

Multidrug-resistant (MDR) Klebsiella pneumoniae is a severe threat to public health worldwide. Worryingly, colistin resistance, one of the last-line antibiotics for the treatment of MDR K. pneumoniae infection, has been increasingly reported. This study aims to investigate the emergence of evolved c...

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Detalles Bibliográficos
Autores principales: Kong, Yingying, Li, Chao, Chen, Hangfei, Zheng, Wei, Sun, Qingyang, Xie, Xinyou, Zhang, Jun, Ruan, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256851/
https://www.ncbi.nlm.nih.gov/pubmed/34234754
http://dx.doi.org/10.3389/fmicb.2021.656610