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A Bayesian inference transcription factor activity model for the analysis of single-cell transcriptomes

Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful experimental approach to study cellular heterogeneity. One of the challenges in scRNA-seq data analysis is integrating different types of biological data to consistently recognize discrete biological functions and regulatory mechanisms...

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Detalles Bibliográficos
Autores principales: Gao, Shang, Dai, Yang, Rehman, Jalees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256867/
https://www.ncbi.nlm.nih.gov/pubmed/34193535
http://dx.doi.org/10.1101/gr.265595.120