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HIF-1α Affects the Neural Stem Cell Differentiation of Human Induced Pluripotent Stem Cells via MFN2-Mediated Wnt/β-Catenin Signaling

Hypoxia-inducible factor 1α (HIF-1α) plays pivotal roles in maintaining pluripotency, and the developmental potential of pluripotent stem cells (PSCs). However, the mechanisms underlying HIF-1α regulation of neural stem cell (NSC) differentiation of human induced pluripotent stem cells (hiPSCs) rema...

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Detalles Bibliográficos
Autores principales: Cui, Peng, Zhang, Ping, Yuan, Lin, Wang, Li, Guo, Xin, Cui, Guanghui, Zhang, Yanmin, Li, Minghua, Zhang, Xiaowei, Li, Xiaoqiang, Yin, Yuxin, Yu, Zhendong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256873/
https://www.ncbi.nlm.nih.gov/pubmed/34235146
http://dx.doi.org/10.3389/fcell.2021.671704