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ReporterSeq reveals genome-wide dynamic modulators of the heat shock response across diverse stressors

Understanding cellular stress response pathways is challenging because of the complexity of regulatory mechanisms and response dynamics, which can vary with both time and the type of stress. We developed a reverse genetic method called ReporterSeq to comprehensively identify genes regulating a stres...

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Detalles Bibliográficos
Autores principales: Alford, Brian D, Tassoni-Tsuchida, Eduardo, Khan, Danish, Work, Jeremy J, Valiant, Gregory, Brandman, Onn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257254/
https://www.ncbi.nlm.nih.gov/pubmed/34223816
http://dx.doi.org/10.7554/eLife.57376