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Mechanism of Ferroptosis and Its Role in Type 2 Diabetes Mellitus

Ferroptosis is a novel form of nonapoptotic regulated cell death (RCD). It features iron-dependent lipid peroxide accumulation accompanied by inadequate redox enzymes, especially glutathione peroxidase 4 (GPX4). RAS-selective lethal 3 (RSL3), erastin, and ferroptosis inducing 56 (FIN56) induce ferro...

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Detalles Bibliográficos
Autores principales: Sha, Wenxin, Hu, Fei, Xi, Yang, Chu, Yudong, Bu, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257355/
https://www.ncbi.nlm.nih.gov/pubmed/34258295
http://dx.doi.org/10.1155/2021/9999612