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NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma

Current studies on tumor progression focus on the roles of cytokines in the tumor microenvironment (TME), and recent research shows that transforming growth factor-β1 (TGF-β1) released from TME plays a pivotal role in tumor development and malignant transformation. The alteration in cellular metabol...

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Detalles Bibliográficos
Autores principales: Su, Xiangsheng, Yang, Yihang, Guo, Changfa, Zhang, Rui, Sun, Shicheng, Wang, Yanjun, Qiao, Qiujiang, Fu, Yibing, Pang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257383/
https://www.ncbi.nlm.nih.gov/pubmed/34257808
http://dx.doi.org/10.1155/2021/5549047