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NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma
Current studies on tumor progression focus on the roles of cytokines in the tumor microenvironment (TME), and recent research shows that transforming growth factor-β1 (TGF-β1) released from TME plays a pivotal role in tumor development and malignant transformation. The alteration in cellular metabol...
Autores principales: | Su, Xiangsheng, Yang, Yihang, Guo, Changfa, Zhang, Rui, Sun, Shicheng, Wang, Yanjun, Qiao, Qiujiang, Fu, Yibing, Pang, Qi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257383/ https://www.ncbi.nlm.nih.gov/pubmed/34257808 http://dx.doi.org/10.1155/2021/5549047 |
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