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Peptide inhibitors against SARS-CoV-2 2′-O-methyltransferase involved in RNA capping: A computational approach

The COVID-19 pandemic is still evolving and is caused by SARS-CoV-2. The 2′-O-methyltransferase (nsp16) enzyme is crucial for maintaining the stability of viral RNA for effective translation of viral proteins and its life cycle. Another protein, nsp10, is important for enzymatic activity of nsp16. A...

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Detalles Bibliográficos
Autores principales: Dutta, Mainak, Iype, Eldhose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257429/
https://www.ncbi.nlm.nih.gov/pubmed/34250275
http://dx.doi.org/10.1016/j.bbrep.2021.101069