Cargando…

CDK9 keeps RNA polymerase II on track

Cyclin-dependent kinase 9 (CDK9), the kinase component of positive transcription elongation factor b (P-TEFb), is essential for transcription of most protein-coding genes by RNA polymerase II (RNAPII). By releasing promoter-proximally paused RNAPII into gene bodies, CDK9 controls the entry of RNAPII...

Descripción completa

Detalles Bibliográficos
Autor principal: Egloff, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257543/
https://www.ncbi.nlm.nih.gov/pubmed/34146121
http://dx.doi.org/10.1007/s00018-021-03878-8