NF-κB is involved in the regulation of autophagy in mutant p53 cells in response to ionizing radiation

Chemotherapy and ionizing radiation (IR) can induce autophagy in tumor cells. Here, we report that the level of autophagy in tumor cells was related to the background of p53 gene that NF-κB acts as a negative regulator of autophagy in mutant p53 (p53-R273H) cells, and that acetylation was involved i...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Ying, Zuo, Wenqing, Shen, Xiao, Liu, Yali, Zhao, Yifan, Xiong, Yajie, Cao, Huimin, Wang, Yan, Liang, Zhongqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257568/
https://www.ncbi.nlm.nih.gov/pubmed/34226514
http://dx.doi.org/10.1038/s41420-021-00533-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257568/
https://www.ncbi.nlm.nih.gov/pubmed/34226514
http://dx.doi.org/10.1038/s41420-021-00533-w

Ejemplares similares