Chromatin states shaped by an epigenetic code confer regenerative potential to the mouse liver

We hypothesized that the highly controlled pattern of gene expression that is essential for liver regeneration is encoded by an epigenetic code set in quiescent hepatocytes. Here we report that epigenetic and transcriptomic profiling of quiescent and regenerating mouse livers define chromatin states...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Chi, Macchi, Filippo, Magnani, Elena, Sadler, Kirsten C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257577/
https://www.ncbi.nlm.nih.gov/pubmed/34226551
http://dx.doi.org/10.1038/s41467-021-24466-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257577/
https://www.ncbi.nlm.nih.gov/pubmed/34226551
http://dx.doi.org/10.1038/s41467-021-24466-1

Ejemplares similares