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Chromatin states shaped by an epigenetic code confer regenerative potential to the mouse liver
We hypothesized that the highly controlled pattern of gene expression that is essential for liver regeneration is encoded by an epigenetic code set in quiescent hepatocytes. Here we report that epigenetic and transcriptomic profiling of quiescent and regenerating mouse livers define chromatin states...
Autores principales: | Zhang, Chi, Macchi, Filippo, Magnani, Elena, Sadler, Kirsten C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257577/ https://www.ncbi.nlm.nih.gov/pubmed/34226551 http://dx.doi.org/10.1038/s41467-021-24466-1 |
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