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Disruption of nucleocytoplasmic trafficking as a cellular senescence driver

Senescent cells exhibit a reduced response to intrinsic and extrinsic stimuli. This diminished reaction may be explained by the disrupted transmission of nuclear signals. However, this hypothesis requires more evidence before it can be accepted as a mechanism of cellular senescence. A proteomic anal...

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Detalles Bibliográficos
Autores principales: Park, Ji-Hwan, Ryu, Sung Jin, Kim, Byung Ju, Cho, Hyun-Ji, Park, Chi Hyun, Choi, Hyo Jei Claudia, Jang, Eun-Jin, Yang, Eun Jae, Hwang, Jeong-A, Woo, Seung-Hwa, Lee, Jun Hyung, Park, Ji Hwan, Choi, Kyung-Mi, Kwon, Young-Yon, Lee, Cheol-Koo, Park, Joon Tae, Cho, Sung Chun, Lee, Yun-Il, Lee, Sung Bae, Han, Jeong A., Cho, Kyung A, Kim, Min-Sik, Hwang, Daehee, Lee, Young-Sam, Park, Sang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257587/
https://www.ncbi.nlm.nih.gov/pubmed/34188179
http://dx.doi.org/10.1038/s12276-021-00643-6