Structural basis of ethnic-specific variants of PAX4 associated with type 2 diabetes

Recently, we conducted genome-wide association studies of type 2 diabetes (T2D) in a Japanese population, which identified 20 novel T2D loci that were not associated with T2D in Europeans. Moreover, nine novel missense risk variants, such as those of PAX4, were not rare in the Japanese population, b...

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Detalles Bibliográficos
Autores principales: Hosoe, Jun, Suzuki, Ken, Miya, Fuyuki, Kato, Takashi, Tsunoda, Tatsuhiko, Okada, Yukinori, Horikoshi, Momoko, Shojima, Nobuhiro, Yamauchi, Toshimasa, Kadowaki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Data Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257626/
https://www.ncbi.nlm.nih.gov/pubmed/34226521
http://dx.doi.org/10.1038/s41439-021-00156-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257626/
https://www.ncbi.nlm.nih.gov/pubmed/34226521
http://dx.doi.org/10.1038/s41439-021-00156-8

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