Biological importance of OCT transcription factors in reprogramming and development

Ectopic expression of Oct4, Sox2, Klf4 and c-Myc can reprogram somatic cells into induced pluripotent stem cells (iPSCs). Attempts to identify genes or chemicals that can functionally replace each of these four reprogramming factors have revealed that exogenous Oct4 is not necessary for reprogrammin...

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Detalles Bibliográficos
Autores principales: Kim, Kee-Pyo, Han, Dong Wook, Kim, Johnny, Schöler, Hans R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257633/
https://www.ncbi.nlm.nih.gov/pubmed/34117345
http://dx.doi.org/10.1038/s12276-021-00637-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257633/
https://www.ncbi.nlm.nih.gov/pubmed/34117345
http://dx.doi.org/10.1038/s12276-021-00637-4

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